Basic Principles Of Drug Discovery And Development

Author: Benjamin Blass
Publisher: Elsevier
ISBN: 012411525X
Size: 80.67 MB
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The text introduces the fundamental principles of drug discovery and development, also discussing important drug targets by class, in vitro screening methods, medicinal chemistry strategies in drug design, principles in pharmacokinetics and ...

Pharmacokinetics In Drug Discovery And Development

Author: Ronald D. Schoenwald
Publisher: CRC Press
ISBN: 1420010085
Size: 31.12 MB
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After an introduction of basic principles, the book is divided into sections that cover industrial and regulatory applications, clinical applications, and research applications.

Plant Bioactives And Drug Discovery

Author: Valdir Cechinel-Filho
Publisher: John Wiley & Sons
ISBN: 047058226X
Size: 35.52 MB
Format: PDF, ePub
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An edited volume featuring multidisciplinary international contributions from acclaimed scientists researching bioactive natural products, the book provides an incisive overview of one of the most important topics in pharmaceutical studies ...

General And Molecular Pharmacology

Author: Francesco Clementi
Publisher: John Wiley & Sons
ISBN: 1118768590
Size: 76.65 MB
Format: PDF, ePub
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With a focus on functional relationships between drugs and their targets, this book covers basic and general pharmacology, from a cellular and molecular perspective, with particular attention to the mechanisms of drug action – the ...

Genomics In Drug Discovery And Development

Author: Dimitri Semizarov
Publisher: John Wiley & Sons
ISBN: 0470409762
Size: 40.40 MB
Format: PDF, ePub
View: 1922
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Pharmaceutical discovery scientists therefore should take advantage of this book's unique integrated coverage of biomarkers, toxicogenomics, and pharmacogenomics in order to make their own discovery efforts as fruitful as possible.

Cancer Drug Design And Discovery

Author: Stephen Neidle
Publisher: Academic Press
ISBN: 0123972280
Size: 55.12 MB
Format: PDF, ePub
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The trends that were apparent in 2008 are even more marked in 2013, with
advances in our basic understanding of the molecular (and, increasingly, genetic
) basis of human cancers being translated into new therapeutic agents. Perhaps
the best example of this is in malignant melanoma, where the identification of
oncogenic mutations in the B-rafgene has led to the development of effective
inhibitors, some of which have shown remarkable effectiveness in clinical use,
although the ...

Kinetics Of Enzyme Action

Author: Ross L. Stein
Publisher: John Wiley & Sons
ISBN: 9781118084403
Size: 59.17 MB
Format: PDF, Mobi
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Some of the highlights in this book include: A detailed description of enzyme kinetics as applied to drug discovery A comprehensive collection of theory and pragmatic approaches to guide readers in the science of performing detailed enzyme ...