Drug Like Properties

Author: Li Di
Publisher: Academic Press
ISBN: 0128013222
Size: 28.67 MB
Format: PDF, Mobi
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Of the thousands of novel compounds that a drug discovery project team invents and that bind to the therapeutic target, only a fraction have sufficient ADME (absorption, distribution, metabolism, elimination) properties, and acceptable ...

Drug Like Properties Concepts Structure Design And Methods

Author: Li Di
Publisher: Academic Press
ISBN: 0080557619
Size: 80.19 MB
Format: PDF
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If the properties are weak, the candidate will have a high risk of failure or be less desirable as a drug product. This book is a tool and resource for scientists engaged in, or preparing for, the selection and optimization process.

Drug Like Properties Concepts Structure Design And Methods

Author: Edward Kerns
Publisher: Academic Press
ISBN: 0080951627
Size: 62.46 MB
Format: PDF
View: 2372
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If the properties are weak, the candidate will have a high risk of failure or be less desirable as a drug product. This book is a tool and resource for scientists engaged in, or preparing for, the selection and optimization process.

The Organic Chemistry Of Drug Design And Drug Action

Author: Richard B. Silverman
Publisher: Academic Press
ISBN: 0123820316
Size: 53.80 MB
Format: PDF
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This text is designed for undergraduate and graduate students in chemistry studying medicinal chemistry or pharmaceutical chemistry; research chemists and biochemists working in pharmaceutical and biotechnology industries.

Fragment Based Drug Discovery

Author: Daniel A. Erlanson
Publisher: John Wiley & Sons
ISBN: 352733775X
Size: 16.74 MB
Format: PDF, ePub, Docs
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Written by the pioneers in the field, this book provides a comprehensive overview of current methods and applications of fragment-based discovery, as well as an outlook on where the field is headed.

Pharmacology For Chemists

Author: Joseph G. Cannon
Publisher: Amer Chemical Society
ISBN: 0841239274
Size: 72.47 MB
Format: PDF, ePub, Docs
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The first portion of this book concentrates on biological/pharmacological principles and concepts, and the second portion demonstrates how these concepts and principles are applicable to the medicinal chemists efforts, by describing some ...

Blood Brain Barrier In Drug Discovery

Author: Li Di
Publisher: John Wiley & Sons
ISBN: 1118788354
Size: 19.41 MB
Format: PDF, Mobi
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Focused on central nervous system (CNS) drug discovery efforts, this book educates drug researchers about the blood-brain barrier (BBB) so they can affect important improvements in one of the most significant – and most challenging – ...

Drug Metabolism And Pharmacokinetics Quick Guide

Author: Siamak Cyrus Khojasteh
Publisher: Springer Science & Business Media
ISBN: 9781441956293
Size: 66.45 MB
Format: PDF, ePub
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This guide provides, for the first time, a completely integrated look at multiple aspects of absorption, distribution, metabolism, and excretion (ADME) science in a summary format that is clear, concise and self-explanatory.

Thermodynamics And Kinetics Of Drug Binding

Author: György Keserü
Publisher: John Wiley & Sons
ISBN: 352733582X
Size: 62.51 MB
Format: PDF, Docs
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Divided into two parts on the thermodynamics and kinetics of drug-receptor interaction, the text provides the conceptual and methodological basis for characterizing binding mechanisms for drugs and other bioactive molecules.

The Practice Of Medicinal Chemistry

Author: Camille Georges Wermuth
Publisher: Elsevier
ISBN: 012417213X
Size: 54.95 MB
Format: PDF, ePub, Mobi
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With topics like high content screening, scoring, docking, binding free energy calculations, polypharmacology, QSAR, chemical collections and databases, and much more, this book is the go-to reference for all academic and pharmaceutical ...