Drug Like Properties

Author: Li Di
Publisher: Academic Press
ISBN: 0128013222
Size: 77.12 MB
Format: PDF, Kindle
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Of the thousands of novel compounds that a drug discovery project team invents and that bind to the therapeutic target, only a fraction have sufficient ADME (absorption, distribution, metabolism, elimination) properties, and acceptable ...

Drug Like Properties Concepts Structure Design And Methods

Author: Li Di
Publisher: Academic Press
ISBN: 0080557619
Size: 69.21 MB
Format: PDF, ePub, Docs
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If the properties are weak, the candidate will have a high risk of failure or be less desirable as a drug product. This book is a tool and resource for scientists engaged in, or preparing for, the selection and optimization process.

Drug Like Properties Concepts Structure Design And Methods

Author: Edward Kerns
Publisher: Academic Press
ISBN: 0080951627
Size: 46.74 MB
Format: PDF, ePub, Docs
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If the properties are weak, the candidate will have a high risk of failure or be less desirable as a drug product. This book is a tool and resource for scientists engaged in, or preparing for, the selection and optimization process.

Drug Metabolism And Pharmacokinetics Quick Guide

Author: Siamak Cyrus Khojasteh
Publisher: Springer Science & Business Media
ISBN: 9781441956293
Size: 31.43 MB
Format: PDF, Mobi
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This guide provides, for the first time, a completely integrated look at multiple aspects of absorption, distribution, metabolism, and excretion (ADME) science in a summary format that is clear, concise and self-explanatory.

Lead Optimization For Medicinal Chemists

Author: Florencio Zaragoza Dörwald
Publisher: John Wiley & Sons
ISBN: 3527645659
Size: 13.66 MB
Format: PDF, ePub, Mobi
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This book is mainly aimed at medicinal chemists, but may also be of interest to graduate students in chemical or pharmaceutical sciences, preparing themselves for a job in the pharmaceutical industry, and to healthcare professionals in need ...

Thermodynamics And Kinetics Of Drug Binding

Author: György Keserü
Publisher: John Wiley & Sons
ISBN: 352733582X
Size: 23.83 MB
Format: PDF, ePub, Mobi
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Divided into two parts on the thermodynamics and kinetics of drug-receptor interaction, the text provides the conceptual and methodological basis for characterizing binding mechanisms for drugs and other bioactive molecules.

The Organic Chemistry Of Drug Design And Drug Action

Author: Richard B. Silverman
Publisher: Academic Press
ISBN: 0123820316
Size: 52.32 MB
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This text is designed for undergraduate and graduate students in chemistry studying medicinal chemistry or pharmaceutical chemistry; research chemists and biochemists working in pharmaceutical and biotechnology industries.

The Practice Of Medicinal Chemistry

Author: Camille Georges Wermuth
Publisher: Elsevier
ISBN: 012417213X
Size: 34.11 MB
Format: PDF, Mobi
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With topics like high content screening, scoring, docking, binding free energy calculations, polypharmacology, QSAR, chemical collections and databases, and much more, this book is the go-to reference for all academic and pharmaceutical ...

A Pharmacology Primer

Author: Terry Kenakin
Publisher: Elsevier
ISBN: 0124076890
Size: 33.48 MB
Format: PDF, ePub, Mobi
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This edition has been thoroughly revised to include material on data-driven drug discovery, biased signaling, structure-based drug design, drug activity screening, drug development (including pharmacokinetics and safety Pharmacology), and ...

Blood Brain Barrier In Drug Discovery

Author: Li Di
Publisher: John Wiley & Sons
ISBN: 1118788354
Size: 80.62 MB
Format: PDF, ePub, Mobi
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Focused on central nervous system (CNS) drug discovery efforts, this book educates drug researchers about the blood-brain barrier (BBB) so they can affect important improvements in one of the most significant – and most challenging – ...