Protein Actions Principles And Modeling

Author: Ivet Bahar
Publisher: Garland Science
ISBN: 1351815016
Size: 77.97 MB
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These chapters illuminate how proteins attain biologically active states and the properties of those states. The book ends with a synopsis the roles of computational biology and bioinformatics in protein science.

Principles Of Protein Structure

Author: Ivet Bahar
Publisher: Garland Science
ISBN: 9780815341772
Size: 59.37 MB
Format: PDF
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These chapters illuminate how proteins attain biologically active states and the properties of those states. The book ends with a synopsis the roles of computational biology and bioinformatics in protein science.

Solvent Dependent Flexibility Of Proteins And Principles Of Their Function

Author: Aleksandr Ivanovich Ki͡a︡ĭvi͡a︡ri͡a︡ĭnen
Publisher: D Reidel Pub Co
ISBN:
Size: 60.97 MB
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The analysis of data obtained by X-ray diffraction, NMR, spin-label, fluorescence,
calorimetric, IR-spectroscopy and other methods, underlies three dynamic
models of protein behavior in solutions: the equilibrium model, the model of
specific protein-ligand complex formation, and the model of enzymatic catalysis.
In contrast to earlier concepts, the main role played in these models is attributed
to the relative correlated fluctuations of domains and entire subunits of a
macromolecule.

Revue Roumaine De Biochimie

Author:
Publisher:
ISBN:
Size: 52.50 MB
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These principles are the first step in understanding the relationships between the
chemical structure and the action of proteins in the organism. In addition,
establishing principles facilitate and ... The following three chapters deal with
some problems concerning the proper protein structure, namely: patterns of
solding and association of polypeptide chains, prediction of secondary structure
of proteins, models of protein structures. Some other important topics covered in
the book are ...

Principles Of Protein Structure

Author: Georg E. Schulz
Publisher: Springer
ISBN:
Size: 55.27 MB
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Many concepts referring to protein action and interaction were introduced in the
course of hemoglobin research. Many concepts and models concerning protein-
ligand interaction and protein- protein interaction were developed during the
history of hemoglobin research: sigmoid binding behavior (674-676); Hill
coefficient (677); successive binding constants for ligands in oligomeric proteins (
678); cooperativity based on conformational changes (679, 680); and allosteric
control of ...

Principles And Practice Of Spine Surgery

Author: Alexander R. Vaccaro
Publisher: Mosby Incorporated
ISBN: 9780323010771
Size: 66.48 MB
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Differential effects and glucocorticoid potentiation of bone morphogenetic protein
action during rat osteoblast differentiation in vitro, Endocrinology 137:3401-3407.
1996. 9. Boden SD et al.: Video-assisted lateral intertransverse process
arthrodesis: validation of a new minimally invasive lumbar spinal fusion
technique in the rabbit and nonhuman primate (rhesus) models. Spine 21:2689-
2697, 1996 1 0. Boden SD. Schimandle JH: Biologic enhancement of spinal
fusion, Spine 20:1 1 ...

Molecular Modeling

Author: Hans-Dieter H?ltje
Publisher: John Wiley & Sons
ISBN: 3527315683
Size: 43.76 MB
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Ideal for beginners, this book explains the basics of modeling in a competent yet easily understandable way, with completely worked-out examples to guide readers to their first modeling experiments.

Protein Folding

Author: Alka Dwevedi
Publisher: Springer
ISBN: 3319125923
Size: 47.22 MB
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The principle guiding protein to fold into its native conformation has been
searched by biochemists, structural biologists, molecular biologists, and recently
by bioinformaticians. They have discovered ... Various theoretical models have
been given to elucidate protein folding pathways and their principles. Theoretical
biologists are trying ... Protein folding is the cooperative action of foldons (small
unfolding/refolding units) which defines the unit steps in folding pathway. There is
stepwise ...

Principles Of Drug Action

Author: William B. Pratt
Publisher:
ISBN:
Size: 24.54 MB
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This theory also was based on the concept that in a multisubunit protein
maintenance of symmetry between subunits is the predominant driving force.
Thus, in either the presence or absence of ligand, the individual subunits within
an oligomer will try to maintain an identity of conformational state. The energy of
interaction at subunit interfaces could be the driving force to achieve
conformational identity among the subunits or symmetry at their interfaces. Such
a model gives rise to a ...

Principles Of Endocrine Pharmacology

Author: John A. Thomas
Publisher: Springer Science & Business Media
ISBN: 1468450360
Size: 53.74 MB
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It has been proposed that the early actions of thyroid hormone are due principally
to protein synthesis brought about by increased transcription of DNA. While this
concept of thyroid hormone action involving early increases in protein synthesis
has been supported by some experimental evidence, it has also been proposed
that the hormone(s) acts directly on intracellular organelles. In vitro experimental
models have provided evidence of interactions between the iodothyronines and ...